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Organic compounds that contain a carboxyl group bonded to an organic functional group; carboxyl groups consist of a carbonyl group bonded to a hydroxy group. Includes compounds that are derived from carboxylic acids.
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UK-101 is a potent, selective inhibitor of the immunoproteasome β1i (LMP2) subunit used as a biochemical probe to study immunoproteasome activity and apoptosis-related pathways.
Potent LMP2 inhibition (IC50 ≈ 104 nM).
High selectivity versus β1c and β5 subunits.
High purity suitable for research use (≈99.6%).
Soluble in DMSO (≈7.3 mg/mL); may require warming or sonication.
Supplied in small quantities appropriate for laboratory assays.
Commonly used in biochemical assays and apoptosis research.
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